Quantal ventilatory variability during spontaneous breathing anaesthesia

Quantal ventilatory variability during spontaneous breathing anaesthesia.

BACKGROUND Cardioventilatory coupling is the triggering of inspiratory onset by preceding cardiac activity. We have observed two forms of coupling with a bimodal ('quantal') variation of respiratory period. METHODS We investigated the variables of inspiratory duration (TI), expiratory duration (TE), and tidal volume (VT) where respiratory period variation was bimodal. In 25 anaesthetized spon...

Neurally adjusted ventilatory assist feasibility during anaesthesia

Data are expressed as median (IQR). Data are expressed as median (IQR). CVvt%, coefficient of variation of the tidal volume expressed as percentage.

Model-based characterization of ventilatory stability using spontaneous breathing.

Cyclic ventilatory instabilities are widely attributed to an increase in the sensitivity or loop gain of the chemoreflex feedback loop controlling ventilation. A major limitation in the conventional characterization of this feedback loop is the need for labor-intensive methodologies. To overcome this limitation, we developed a method based on trivariate autoregressive modeling using ventilation...

Preserving spontaneous breathing during mechanical ventilatory support: an old yet fascinating story

Facilitation of early spontaneous breathing activity is the most important measure to shorten weaning and avoid ventilator-induced lung injury and diaphragmatic injury in mechanically ventilated patients. However, the optimal degree of spontaneous muscle activity and ventilator support remains to be determined. Furthermore, effectiveness in relation to the pathophysiology of respiratory failure...

The Breathing-Book Spontaneous breathing during artificial ventilation